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The Baby Bio Bank-A Legacy for Researchers Worldwide into Common Complications of Pregnancy

Abstract

Sayeda Abu-Amero, Anna Thomas, Shawnelle White, Katherine Rogers, Ana Maria Perez Miranda, Nita Solanky, Lydia Leon, Charalambos Demetriou, Xiayi Ke, Sam Stanier, Ben Stanier, Mr Harry Costello Miss Samrawit Tzehaie, Ms Lara Al-Olabi, Catherine Williamson, Mark Johnson, Lesley Regan, and Gudrun E Moore

Two London Universities, University College London and Imperial College London, have established a biobank as a resource for investigating the four main complications of pregnancy (recurrent miscarriage, preterm birth, fetal growth restriction (FGR) and pre-eclampsia), that collectively affect about 20% of families trying to conceive. Samples are being taken from the three key members of the family, mother, father and baby, allowing hereditary factors from both parents to be tracked. Additional samples are being stored to allow parallel analysis of the functional mechanisms of pregnancy including the epigenetic, anatomical, physiological and even metabolic causes for the high loss of fecundity in man. http://www.ucl.ac.uk/babybiobank.

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