Goe Zavros
The prevalence of overweight and obesity has reached epidemic proportions worldwide, leading to various health complications and reduced quality of life. Weight loss interventions, including hypocaloric diets, are commonly prescribed to individuals with excess body weight. However, these interventions often result in a reduction in Resting Metabolic Rate (RMR), which can hinder weight loss efforts. Additionally, alterations in thyroid function, physical fitness, and functional capacity are frequently observed in overweight and obese individuals. This has led researchers to explore the potential benefits of co-supplementation with specific nutrients to mitigate these negative effects. One such combination is zinc and selenium, which have been implicated in regulating metabolic rate, thyroid function, and overall health. This article aims to discuss the impact of co-supplementation with zinc and selenium on RMR, thyroid function, physical fitness, and functional capacity in overweight and obese individuals on a hypocaloric diet based on a randomized, double-blind, and placebo-controlled trial.
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