திசு அறிவியல் மற்றும் பொறியியல் இதழ்

Bio Technological Intervention with Platelet Rich Plasma for Assisted Regeneration of Sole

Abstract

Sandeep Shrivastava, Sparsh Naik, Bhushan Patil, Pankaj Kharabe, Anurag Gupta and Swapnil Joshi

With the advent of Regenerative medicine products in medicine, newer solutions are getting evolved for complex conditions. The Cellular therapies offer a new ray of hope by inducing regeneration of tissue at the site of damage. The cellular therapy led by platelet rich plasma (PRP) is one such key regenerative product. But there is a huge variability in its usage, particularly for wounds. The standardisation for clinical usage is not yet evolved, hence limiting the clinical application of the same. The authors have developed a standard protocol “STARS” therapy, which utilises PRP as biotechnological tool, re-engineering the damaged tissue and gradually assisting the regeneration. In this study we report 8 cases of wounds / ulcers over the sole being treated by it. The results are excellent and offer a milestone solution to non-healing wounds/ ulcers over soles. These wounds are otherwise, very difficult to treat particularly as they are associated with high risks factors such as infection, Diabetes and old age. They are under constant pressure due to weight bearing and give way easily and do not heal. The bioenginreeing of the sole tissues through PRP led STARS intervention is safe, effective and easily reproducible.