Sohini Roy, Debarati Chattopadhyay, Kaushik Dewan, Keya Sarkar Biswas and Uttam Kumar Nath
Giant congenital melanocytic nevi a ≥ 20 cm is rare in adolescents and adults. Here we present a case of subcutaneous melanoma developing in congenital giant naevus with complete regression of superficial dermoepidermal part. A 17 yr old girl presented with a painless and gradually increasing swelling in her right temporal region on pre-existing giant congenital menocytic naevus (GCMN) on right hemiface. FNAC proved the case as malignant melanoma of temporal region with metastatic deposit in cervical lymph node. On histopathological examination it was found that the melanoma arising deep in the subcutaneous tissue with extensive involvement of deeper structures, extensive metastasis of cervical lymph nodes, salivary glands, deeper soft tissues with spontaneous regression of superficial epidermal and dermal part. Though regression is seen in melanomas, spontaneous regression has been mostly seen in melanomas with only intraepidermal component.
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