Zahra Batool and Asma Haque
The ALAD (Aminolevulinic Acid Dehydratase) gene polymorphism is linked with the accumulation of lead in the bone, blood and the other internal organs and it may predispose for many critical symptoms in the lead exposed persons. The aim of this study is to determine the primary, secondary and tertiary structure of lead. This enzyme is susceptible towards the toxic effect of lead. Primary structure prediction was done by Protparam tool, Compute PI/MW tool, Proscale tool. Secondary structure prediction was done by Self –optimize prediction method (SOPMA) tool, Porter tool. Tertiary structure prediction was done by protein structure prediction server. Domain was determined by Simple Modular Architecture Research (SMART) tool.
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