Yun Zhou*, Yuliang Chen, Wenfeng Lu, Xueni Wang, Li Cai, Xuyang Guo, Chenghui Zhong, Binyan Zou, Xintong Chen, Lan Qiu, Han Zhang and Xiaoliang Li
Background: Daily step count was associated with various health outcomes. However, the quantitative relationship between daily step count and lung function among general population is unclear to date.
Methods: We conducted a panel study with repeated measurement of daily step counts and lung function parameters in consecutive 11 days among 16 healthy male college students in a self-controlled study design. Linear mixed-effect model was used to assess the dose-response relationship between daily step count and lung function parameters.
Results: Compared with control days, subjects in intervention days had lower daily step counts and lung function parameters. Nonlinear associations of daily step count with FEV0.5, FEV0.5/FVC, and FEV1.0/FVC were observed in all observations, but become insignificant in subgroups of step count ≤ 8000 or >8000. Significant linear dose-response relationships were observed in those taking daily step counts ≤ 8000, showing that each 1000-increase in daily step was significantly associated with 36.81 ml, 20.29 ml, 1.36%, 0.48%, 1.88%, 1.38%, 2.06% and 0.76% increase in FEV0.5, FEV1.0, FEV0.5/FVC, FEV1.0/FVC, MMF%pred, FEF25%pred, FEF50%pred, and FEF75%pred, respectively.
Conclusion: Increased daily step count benefits lung function among healthy male adults, though the excess benefit was limited when taking more than 8000 steps per day.
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